Gene Therapy
Study findings from University of Pittsburgh broaden understanding of gene therapy
Published in Gene Therapy Weekly, October 28th, 2010
New research, 'Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector,' is the subject of a report. "To assist in screening existing drugs for use as potential radioprotectors, we used a human unbiased 16,560 short interfering RNA (siRNA) library targeting the druggable genome. We performed a synthetic protection screen that was designed to identify genes that, when silenced, protected human glioblastoma T98G cells from gamma-radiation-induced cell death," scientists in the United States report.
"We identified 116 candidate protective genes, then identified 10 small molecule inhibitors of 13 of these candidate gene products and...
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Source: Gene Therapy Weekly (2010-10-28)
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