Anemia
Research results from University of Washington, Department of Medicine update knowledge of anemia
Published in Gene Therapy Weekly, November 11th, 2010
Current study results from the report, 'Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector,' have been published. According to a study from the United States, "One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation. To minimize this damage, we have developed a brief transduction procedure for lentivirus vector-mediated transduction of hematopoietic progenitor cells from patients with Fanconi anemia complementation group A (FANCA)."
"The...
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Source: Gene Therapy Weekly (2010-11-11)
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