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Small Interference RNAs (siRNAs)

Research from Seoul National University, Cancer Research Institute SAS in the area of small interference RNAs (sirnas) published

Published in Gene Therapy Weekly, December 2nd, 2010

2010 DEC 2 -- Scientists discuss in 'RNA interference-directed caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis' new findings in small interference rnas (sirnas). According to a study from Seoul, Korea, "Human renal cell carcinoma (HRCC) is characterized by a high level of resistance to all treatment modalities. Therefore, the investigation of global gene expression in HRCC might help understand its biologic behavior and develop treatment strategies."

"Using cDNA microarray analysis, we initially compared gene expression profiles between HRCCs and adjacent normal tissues, and found that 87 were...

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