Diabetes
Study results from Qingdao University, Department of Pediatrics update understanding of diabetes
Published in Gene Therapy Weekly, December 2nd, 2010
2010 DEC 2 -- A report, 'Recombinant adenoviral expression of IL-10 protects beta cell from impairment induced by pro-inflammatory cytokine,' is newly published data in Molecular and Cellular Biochemistry. According to a study from Qingdao, People's Republic of China, "Interleukin-10 (IL-10) is a pleiotropic immunosuppressive and immunostimulatory cytokine. In autoimmune diabetes of the nonobese diabetic (NOD) mouse, IL-10 has exhibited paradoxical effects."
"Systemic IL-10 expression prevented or delayed diabetes onset in NOD mice while local expression of IL-10 did not. As antigen-presenting cells (APCs) play a central role in the generation of...
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Source: Gene Therapy Weekly (2010-12-02)
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