Small Interference RNAs (siRNAs)
Data from V. Digiacomo et al provide new insights into small interference RNAs (sirnas)
Published in Gene Therapy Weekly, December 9th, 2010
2010 DEC 9 -- "H9c2 are rat heart embryonic myoblasts, with skeletal muscle properties, which terminally differentiate by fusing and forming multinucleated myotubes. Here we investigated the possible involvement of Protein Kinases C (PKCs) in H9c2 cell differentiation and explored the interplay of these enzymes both with reactive oxygen species (ROS), upstream physiological mediators of cell differentiation, and with nitric oxide(NO), downstream target of PKC activation, known for being involved in apoptosis induction in differentiated myoblasts," scientists writing in the journal Differentiation report.
"Cells were induced to differentiate (6 days)...
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Source: Gene Therapy Weekly (2010-12-09)
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