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Gene Therapy

Research on gene therapy reported by scientists at University of Cambridge, Cambridge Institute for Medical Research

Published in Gene Therapy Weekly, December 16th, 2010

2010 DEC 16 -- Data detailed in 'A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients' have been presented. According to recent research from Cambridge, the United Kingdom, "The T-cell oncogene Lim-only 2 (LMO2) critically influences both normal and malignant haematopoiesis. LMO2 is not normally expressed in T cells, yet ectopic expression is seen in the majority of T-acute lymphoblastic leukaemia (T-ALL) patients with specific translocations involving LMO2 in only a subset of these patients."

"Ectopic lmo2 expression in thymocytes of...

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