Gene Therapy
Data on gene therapy described by investigators at Research Center
Published in Gene Therapy Weekly, December 23rd, 2010
2010 DEC 23 -- Fresh data on gene therapy are presented in the report 'Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected].' "We reported previously that the forced expression of the chemokine BRAK, also called CXCL14 in head and neck squamous cell carcinoma (HNSCC) cells decreased the rate of tumor formation and size of tumor xenografts compared with mock-vector treated cells in athymic nude mice or in severe combined immunodeficiency mice. This suppression occurred even though the growth rates of these cells were the same under in vitro culture conditions, suggesting that a high expression level of the gene in tumor cells is...
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Source: Gene Therapy Weekly (2010-12-23)
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