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Antisense Technology

Findings from M. Parrybillings and co-researchers advance knowledge in antisense technology

Published in Gene Therapy Weekly, December 30th, 2010

2010 DEC 30 -- "Asthma and COPD are significant lung diseases for which anti-inflammatories, including inhaled corticosteroids and leukotriene-targeted drugs, represent a key element of current therapy. Oligonucleotides comprise a diverse family of emerging drug candidates for the treatment of these diseases," scientists writing in the journal Current Opinion in Investigational Drugs report.

"There is a commonality in the chemistry of oligonucleotide drug molecules but, importantly, individual candidates are distinct in their molecular targets and also possess different mechanisms of action. Oligonucleotides may be divided in two groups based on...

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