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Cancer Gene Therapy

Recent findings from South China Sea Institute of Oceanology highlight research in cancer gene therapy

Published in Gene Therapy Weekly, December 30th, 2010

2010 DEC 30 -- Fresh data on cancer gene therapy are presented in the report 'A new 1,4-diazepine from South China Sea marine sponge Callyspongia species.' "A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), andcyclo-(S-Pro-R-Tyr) (5)," scientists writing in the journal Molecules report.

"The new structure was determined on the basis of NMR and MS analysis, and the absolute stereochemistry was defined by NOESY spectroscopy and optical rotation. The structures of...

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