Small Interference RNAs (siRNAs)
Investigators at Cancer Research UK London Research Institute have published new data on small interference RNAs (sirnas)
Published in Gene Therapy Weekly, January 6th, 2011
2011 JAN 6 -- Research findings, 'Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes,' are discussed in a new report. "The immune cells named T lymphocytes circulate around the body fulfilling their role in immunosurveillance by monitoring the tissues for injury or infection. To migrate from the blood into the tissues, they make use of the integrin LFA-1 which is exclusively expressed by immune cells," investigators in London, the United Kingdom report.
"These highly motile cells attach and migrate on substrates expressing the LFA-1 ligand ICAM-1. The molecular events signaling LFA-1 activation and adhesion are now reasonably well...
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Source: Gene Therapy Weekly (2011-01-06)
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