Gene Therapy

Recent findings from University of Ulsan, Medical Department highlight research in gene therapy

Published in Gene Therapy Weekly, January 13th, 2011

2011 JAN 13 -- "The hepatitis C virus (HCV) is a continuing threat to public health. The systemic administration of interferon alpha with ribavirin is the only currently approved treatment," scientists in Seoul, South Korea report.

"However, this treatment is associated with a wide spectrum of systemic side effects that limits its effectiveness; thus, there is an urgent need for new treatment modalities. In this study, we describe a novel anti-HCV strategy employing a recombinant transcription factor that we have engineered in such a way that NS3/4a viral protease controls its intracellular localization, thereby restoring interferon secretion specifically...

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Source: Gene Therapy Weekly (2011-01-13)

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