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Inflammation Mediators

Researchers from National Heart Lung and Blood Institute Describe Findings in Inflammation Mediators

Published in Gene Therapy Weekly, January 20th, 2011

2011 JAN 20 -- Current study results from the report, 'IL-21 and T follicular helper cells,' have been published. "Upon encounter with antigen, CD4(+) T cells differentiate into effector T(h) subsets with distinctive functions that are related to their unique cytokine profiles and anatomical locations. One of the most important T(h) functions is to provide signals to developing B cells that induce specific and appropriate antibody responses," investigators in the United States report.

"The major CD4(+) T cell subset that helps B cells is the T follicular helper (T(FH)) cell, whose expression of the chemokine receptor CXCR5 [chemokine (C-X-C motif) receptor...

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