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Cancer Gene Therapy

Studies from University of Cincinnati, Department of Environmental Health Add New Findings in the Area of Cancer Gene Therapy

Published in Gene Therapy Weekly, January 20th, 2011

2011 JAN 20 -- Scientists discuss in 'The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis' new findings in Cancer Gene Therapy. According to a study from the United States, "The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the biological and toxic effects of its xenobiotic ligands. Previous cell culture studies have shown that, in addition to controlling the xenobiotic detoxification response, AHR activation leads to G0-G1 arrest, diminished capacity for DNA replication, and inhibition of cell proliferation."

"In fact, recent work from our own and from other laboratories suggests...

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