Small Interference RNAs (siRNAs)
Researchers from Chiba University, Department of Molecular Describe Findings in Small Interference RNAs (siRNAs)
Published in Gene Therapy Weekly, February 3rd, 2011
2011 FEB 3 -- New research, 'An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer,' is the subject of a report. "Deregulation of protein synthesis plays a critical role in cell transformation. Several translation initiation factors (eIFs) have been implicated in malignant transformation; thus, suppression of eIFs could be a potential cancer therapy if cancer cells are selectively killed without damaging healthy cells," investigators in Chiba, Japan report.
"One of the potential molecular targets is a cancer-specific splicing variant. We have previously shown...
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Source: Gene Therapy Weekly (2011-02-03)
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