Lymphoma
Studies from Albert Einstein College of Medicine, College of Medicine Have Provided New Data on Lymphoma
Published in Gene Therapy Weekly, February 3rd, 2011
2011 FEB 3 -- "Deoxycytidine deaminase enzyme activity was reduced in lysates of human leukemic THP1 cells 24 h after transfection with siRNA designed to inhibit cell synthesis of heat shock protein 70 (Hsp70)1a and Hsp701b. The cytidine deaminase enzyme activity from the cell lysates was purified from an affinity column which contained bound single-stranded oligodeoxycytidylic acid," scientists in the United States report.
"Deficient enzyme activity in certain elution fractions from the siRNA-transfected cells was restored by including recombinant HSP 70 in the assays. Enzyme activity in some other fractions was increased after siRNA transfection....
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Source: Gene Therapy Weekly (2011-02-03)
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