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Melanomas

Research Reports from O. Berthier-Vergnes and Co-Authors Provide New Insights into Melanomas

Published in Gene Therapy Weekly, February 3rd, 2011

2011 FEB 3 -- Researchers detail in 'Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion,' new data in Melanomas. According to a study from Lyon, France, "Metastatic melanoma requires early detection, being treatment resistant. However, the earliest events of melanoma metastasis, and especially of dermal invasion, remain ill defined."

"AND METHODS: Gene expression profiles of two clonal subpopulations, selected from the same human melanoma cell line, but differing in ability to cross the dermal-epidermal junction in skin reconstructs, were compared by oligonucleotide microarray. Of...

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