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Breast Cancer

Research from Taipei Medical University in the Area of Breast Cancer Published

Published in Gene Therapy Weekly, February 10th, 2011

2011 FEB 10 -- According to a study from Taipei, Taiwan, "Previous studies have demonstrated that the persistent exposure of human bronchial epithelial cells to nicotine (Nic) through nicotinic acetylcholine receptors increases cyclin D1 promoter activity and protein expression. The main purpose of this study is to elucidate the carcinogenic role of cyclin D3, which is involved in breast tumorigenesis when induced by Nic."

"Real-time PCR analysis revealed that cyclin D3 is highly expressed at the mRNA level in surgically dissected breast tumor tissue, compared to the surrounding normal tissue (tumor/normal fold ratio = 17.93, n = 74). To test whether...

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