Angiogenesis
Research from University Medical Center, Comprehensive Cancer Center in the Area of Angiogenesis Published
Published in Gene Therapy Weekly, February 10th, 2011
2011 FEB 10 -- Investigators publish new data in the report 'Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1.' "Oncolytic viral (OV) therapy is a promising therapeutic modality for brain tumors. Vasculostatin (Vstat120) is the cleaved and secreted extracellular fragment of brain-specific angiogenesis inhibitor 1 (BAI1), a brain-specific receptor," scientists in the United States report.
"To date, the therapeutic efficacy of Vstat120 delivery into established tumors has not been investigated. Here we tested the therapeutic efficacy of combining Vstat120 gene delivery in conjunction with OV therapy. We constructed RAMBO...
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Source: Gene Therapy Weekly (2011-02-10)
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