Macrophages
Research on Macrophages Reported by Scientists at Okayama University
Published in Gene Therapy Weekly, February 24th, 2011
2011 FEB 24 -- Researchers detail in 'CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP),' new data in Macrophages. According to recent research from Okayama, Japan, "CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes endochondral ossification. However, the role of CCN2 in the replacement of hypertrophic cartilage with bone is still unclear."
"The phenotype of Ccn2 null mice, having an expanded hypertrophic zone, indicates that the resorption of the cartilage extracellular matrix is impaired therein. Therefore, we...
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Source: Gene Therapy Weekly (2011-02-24)
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