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Small Interference RNAs (siRNAs)

Scientists at University of Hong Kong, Department of Surgery Discuss Research in Small Interference RNAs (siRNAs)

Published in Gene Therapy Weekly, March 10th, 2011

2011 MAR 10 -- Fresh data on Small Interference RNAs (siRNAs) are presented in the report 'NF-'B targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors.' According to a study from People's Republic of China, "Cigarette smoke is one of the risk factors for gastric cancer and nicotine has been reported to promote tumor growth. Deregulation of microRNA (miRNA) and cyclooxygenase-2 (COX-2) expressions are hallmarks of many cancers including gastric cancer."

"Here, we used an miRNA array platform covering a panel of 95 human miRNAs to examine the expression profile in nicotine-treated gastric cancer cells. We found that miR-16 and...

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