Breast Cancer

Recent Studies from Wayne State University Add New Data to Breast Cancer

Published in Gene Therapy Weekly, March 10th, 2011

2011 MAR 10 -- According to a study from the United States, "Platelet-derived growth factor-D (PDGF-D) has been linked with several human malignancies; however, its role in breast cancer progression is not known. We found that PDGF-D expressing breast cancer cell lines MDA-MB-231 and SUM-149 are more invasive compared to cell lines with little or no expression of PDGF-D such as MDA-MB-468 and MCF-7 cells."

"Over-expression of PDGF-D in PDGF-D low expressing MDA-MB-468 and MCF-7 cells by cDNA transfection showed increased cell proliferation while silencing the expression of PDGF-D by siRNA in PDGF-D high expressing MDA-MB-231 and SUM-149 cells showed...

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Source: Gene Therapy Weekly (2011-03-10)

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