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Cytokines

Research from University of Tor Vergata in the Area of Cytokines Published

Published in Gene Therapy Weekly, March 31st, 2011

2011 MAR 31 -- Investigators publish new data in the report 'Interleukin-25 production is differently regulated by TNF-a and TGF-ß1 in the human gut.' "An altered balance between effector and regulatory factors is supposed to sustain the tissue-damaging immune response in inflammatory bowel disease (IBD). We have recently shown that in IBD, there is a defective synthesis of the counter-regulatory cytokine, interleukin (IL)-25," scientists in Rome, Italy report.

"In this study we investigated factors that control IL-25 production in the gut. IBD patients produced less IL-25 when compared with normal controls. Stimulation of normal intestinal explants...

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