Parasitic Disease
Study Data from Genzyme Provide New Insights into Parasitic Disease
Published in Gene Therapy Weekly, March 31st, 2011
2011 MAR 31 -- Data detailed in 'Cysteine proteases as targets for metal-based drugs' have been presented. According to recent research published in the journal Metallomics, "The discovery of the platinum anticancer drug cisplatin provided a major stimulus for research into metal-based drugs. The molecular target for the platinum agents is DNA; however recent developments in inorganic medicinal chemistry have identified several alternative novel targets for metal-based drugs."
"Biological molecules with essential thiol groups are attractive targets. Thiol-containing molecular targets include the redox enzymes thioredoxin reductase and glutathione...
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Source: Gene Therapy Weekly (2011-03-31)
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