Bioinformatics

New Bioinformatics Data Have Been Reported by Scientists at Indiana University School of Medicine

Published in Gene Therapy Weekly, April 7th, 2011

2011 APR 7 -- New research, 'Identifying viral integration sites using SeqMap 2.0,' is the subject of a report. According to recent research published in the journal Bioinformatics, "Retroviral integration has been implicated in several biomedical applications, including identification of cancer-associated genes and malignant transformation in gene therapy clinical trials."

"We introduce an efficient and scalable method for fast identification of viral vector integration sites from long read high-throughput sequencing. Individual sequence reads are masked to remove non-genomic sequence, aligned to the host genome and assembled into contiguous...

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Source: Gene Therapy Weekly (2011-04-07)

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