Viral Vaccines

New Viral Vaccines Findings from University of Utah Described

Published in Gene Therapy Weekly, April 21st, 2011

2011 APR 21 -- "We present a rapid and quantitative method to physically characterize the structure and stability of viruses. Electrospray differential mobility analysis (ES-DMA) is used to determine the size of capsomers (i.e., hexons) and complete capsids," researchers in Salt Lake City, United States report.

"We demonstrate how to convert the measured mobility size into the icosahedral dimensions of a virus, which for PR772 become 68.4 nm for vertex-to-vertex, 54.4 nm for facet-to-facet, and 58.2 nm for edge-to-edge lengths, in reasonable agreement with dimensions from transmission electron microscopy for other members of the family Tectiviridae (e.g.,...

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Source: Gene Therapy Weekly (2011-04-21)

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