Cancer Vaccines

Study Data from L. Decrausaz et al Provide New Insights into Cancer Vaccines

Published in Gene Therapy Weekly, May 5th, 2011

2011 MAY 5 -- According to recent research from Lausanne, Switzerland, "Cervical cancer results from infection with high-risk type human papillomaviruses (HPV). Therapeutic vaccines aiming at controlling existing genital HPV infections and associated lesions are usually tested in mice with HPV-expressing tumor cells subcutaneously implanted into their flank."

"However, effective vaccine-induced regression of these ectopic tumors strongly contrasts with the poor clinical results of these vaccines produced in patients with HPV-associated genital neoplasia. To assess HPV therapeutic vaccines in a more relevant setting, we have, here, established an orthotopic...

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Source: Gene Therapy Weekly (2011-05-05)

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