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Carcinoid Tumors

Recent Findings in Carcinoid Tumors Described by Researchers from University of Wisconsin School of Medicine and Public Health

Published in Gene Therapy Weekly, May 26th, 2011

2011 MAY 26 -- Investigators publish new data in the report "Focal adhesion kinase, a downstream mediator of Raf-1 signaling, suppresses cellular adhesion, migration, and neuroendocrine markers in BON carcinoid cells. 'We have recently reported that activation of the Raf-1/mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase 1/2 (MEK1/2)/ERK1/2 signaling cascade in gastrointestinal carcinoid cell line (BON) alters cellular morphology and neuroendocrine phenotype. The mechanisms by which Raf-1 mediates these changes in carcinoid cells are unclear," scientists in Madison, United States report.

"Here, we report that activation of...

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