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Oligonucleotides

New Findings from University of California Describe Advances in Oligonucleotides

Published in Gene Therapy Weekly, June 16th, 2011

2011 JUN 16 -- According to recent research from San Francisco, United States, "Oligonucleotide-and polynucleotide-based gene modification strategies were developed as an alternative to transgene-based and classical gene targeting-based gene therapy approaches for treatment of genetic disorders. Unlike the transgene-based strategies, oligo/polynucleotide gene targeting approaches maintain gene integrity and the relationship between the protein coding and gene-specific regulatory sequences."

"Oligo/polynucleotide-based gene modification also has several advantages over classical vector-based homologous recombination approaches. These include essentially...

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