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Small Interference RNAs (siRNAs)

Data on Small Interference RNAs (siRNAs) Published by Researchers at University of Calgary

Published in Gene Therapy Weekly, June 23rd, 2011

2011 JUN 23 -- According to a study from Calgary, Canada, "Interferon-gamma (IFN gamma) is an important immunoregulatory cytokine that can also decrease intestinal epithelial barrier function. Little is known about the intracellular signalling events immediately subsequent to IFN gamma/IFN gamma receptor interaction that mediate increases in epithelial permeability; data that could be used to ablate this effect of IFN gamma while leaving its immunostimulatory effects intact."

"This study assessed the potential involvement of Src family kinases in IFN gamma-induced increases in epithelial permeability using confluent filter-grown monolayers of the human...

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