Stem Cell Research

Data on Stem Cell Research Detailed by Researchers at University of Uppsala

Published in Gene Therapy Weekly, June 23rd, 2011

2011 JUN 23 -- "Numerous studies support a role for Sox2 to keep stem cells and progenitor cells in an immature and proliferative state. Coexpression of Sox2 and GFAP has been found in regions of the adult brain where neural stem cells are present and in human glioma cells," scientists writing in the International Journal of Cancer report.

"In our study, we have investigated the roles of Sox2 and its counteracting partner Sox21 in human glioma cells. We show for the first time that Sox21 is expressed in both primary glioblastoma and in human glioma cell lines. We found that coexpression of Sox2, GFAP and Sox21 was mutually exclusive with expression...

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Source: Gene Therapy Weekly (2011-06-23)

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