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Cancer Gene Therapy

Studies from Y. Zhu and Co-Researchers Yield New Data on Cancer Gene Therapy

Published in Gene Therapy Weekly, June 30th, 2011

2011 JUN 30 -- New investigation results, "Inhibition of the cathepsin cysteine proteases B and K by square-planar cycloaurated gold(III) compounds and investigation of their anti-cancer activity," are detailed in a study published in Journal of Inorganic Biochemistry. "Gold(III) compounds have been examined for potential anti-cancer activity. It is proposed that the molecular targets of these compounds are thiol-containing biological molecules such as the cathepsin cysteine proteases," scientists in Langley, Canada report.

"These enzymes have been implicated in many diseases including cancer. The catalytic mechanism of the cathepsin cysteine...

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