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Alcoholism

Study Results from H. Cornella and Colleagues in the Area of Alcoholism Published

Published in Gene Therapy Weekly, July 7th, 2011

2011 JUL 7 -- Research findings, "Molecular pathogenesis of hepatocellular carcinoma," are discussed in a new report. According to the authors of recent research from Catalonia, Spain, "Hepatocellular carcinoma (HCC) is one of the major causes of death among cirrhotic patients, being viral hepatitis and alcohol abuse, the main risk factors for its development. The introduction of highly sophisticated genomic technologies has spurred extensive research on the molecular pathogenesis of this devastating disease."

"Several signaling cascades have been consistently found dysregulated in HCC (e.g., WNT-ß-catenin, PI3K/AKT/MTOR, RAS/MAPK, IGF, HGF/MET, VEGF,...

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