Osteosarcomas

Studies from Fourth Military Medical University Add New Findings in the Area of Osteosarcomas

Published in Gene Therapy Weekly, July 14th, 2011

2011 JUL 14 -- According to the authors of recent research published in the journal Acta Histochemica, "The dysregulation of signal transducers and activators of transcription 3 (STAT3) has been reported to be associated with tumor progression, angiogenesis and metastasis. The purpose of this study was to analyze the clinical value of STAT3 expression in human osteosarcoma."

"First, semi-quantitative RT-PCR was performed to detect the expression of STAT3 mRNA in normal bone tissues, chondroma tissues and osteosarcoma tissues. Then, immunohistochemistry was performed to detect the expression of STAT3 protein in 76 osteosarcoma tissues and the...

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Source: Gene Therapy Weekly (2011-07-14)

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