Cancer Gene Therapy

Recent Findings in Cancer Gene Therapy Described by Researchers from Chinese Academy of Sciences

Published in Gene Therapy Weekly, July 21st, 2011

2011 JUL 21 -- According to the authors of recent research published in the journal Chembiochem, "Specific detection and in vivo tracing of cancer biomarkers are important for cancer analysis. In this work, a simple and effective strategy for developing peptide probes was established."

"Peptides were rationally designed by using an antisense peptide approach directed towards an extracellular fragment (EL2) of a novel tumor-related protein LAPTM4B. Positional-scanning and stepwise affinity screening was employed to obtain an optimal peptide AP2H (IHGHHIISVG). The dissociation constant between the two small peptides, AP2H and the target EL2, was 5.51...

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Source: Gene Therapy Weekly (2011-07-21)

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