Small Interference RNAs (siRNAs)

New Small Interference RNAs (siRNAs) Study Results Reported from Osaka University

Published in Gene Therapy Weekly, July 21st, 2011

2011 JUL 21 -- According to the authors of recent research from Osaka, Japan, "Aquaporins (AQP) play important roles in water and glycerol transport. We examined whether AQP3 is expressed in primary squamous cell carcinoma (SCC) such as esophageal and oral cancer and lymph node metastasis, and whether AQP3 is a potential target for tumor therapy."

"A high level expression of AQP3 was observed in tumor areas of human primary SCC such as esophageal and lingual cancers, and lymph node metastasis, but was not observed in normal areas. Treatment with pan-AQP inhibitor caused apoptotic cell death on the SCC cell lines in a concentration-dependent manner. Small...

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Source: Gene Therapy Weekly (2011-07-21)

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