Cancer Gene Therapy
Researchers from Faculty of Science Discuss Findings in Cancer Gene Therapy
Published in Gene Therapy Weekly, July 21st, 2011
2011 JUL 21 -- "In this study, the apoptotic mechanism and combinatorial chemotherapeutic effects of the cytotoxic phenylpropanoid compound 1'S-1'-acetoxyeugenol acetate (AEA), extracted from rhizomes of the Malaysian ethnomedicinal plant Alpinia conchigera Griff. (Zingiberaceae), on MCF-7 human breast cancer cells were investigated for the first time. Data from cytotoxic and apoptotic assays such as live and dead and poly-(ADP-ribose) polymerase cleavage assays indicated that AEA was able to induce apoptosis in MCF-7 cells, but not in normal human mammary epithelial cells," researchers in Kuala Lumpur, Malaysia report.
"A microarray global gene expression...
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Source: Gene Therapy Weekly (2011-07-21)
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