Antisense Technology
Study Findings from University of North Carolina Provide New Insights into Antisense Technology
Published in Gene Therapy Weekly, July 28th, 2011
2011 JUL 28 -- Fresh data on Antisense Technology are presented in the report "Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands. 'Selective delivery of antisense or siRNA oligonucleotides to cells and tissues via receptor-mediated endocytosis is becoming an important approach for oligonucleotide-based pharmacology. In most cases receptor targeting has been attained using antibodies or peptide-type ligands," researchers in Chapel Hill, North Carolina report.
"Thus, there are few examples of delivering oligonucleotides using the plethora of small-molecule receptor-specific ligands that currently exist....
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Source: Gene Therapy Weekly (2011-07-28)
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