Cancer Gene Therapy
Research from Catholic University Has Provided New Data on Cancer Gene Therapy
Published in Gene Therapy Weekly, July 28th, 2011
2011 JUL 28 -- Researchers detail in "Detection of low-level KRAS mutations using PNA-mediated asymmetric PCR clamping and melting curve analysis with unlabeled probes," new data in Cancer Gene Therapy. According to the authors of recent research from Seoul, South Korea, "Detection of somatic mutations in clinical cancer specimens is often hampered by excess wild-type DNA. The aim of this study was to develop a simple and economical protocol without using fluorescent probes to detect low-level mutations."
"In this study, we combined peptide nucleic acid (PNA)-clamping PCR with asymmetric primers and a melting curve analysis using an unlabeled detection...
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Source: Gene Therapy Weekly (2011-07-28)
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