Drug Development
Research from New York University School of Medicine Provide New Insights into Drug Development
Published in Gene Therapy Weekly, August 4th, 2011
2011 AUG 4 -- A report, "A cross-talk between NFAT and NF-'B Pathways is Crucial for Nickel-Induced COX-2 expression in Beas-2B cells," is newly published data in Current Cancer Drug Targets. According to the authors of recent research from Tuxedo, New York, "Cyclooxygenase-2 (COX-2) is a critical enzyme implicated in chronic inflammation-associated cancer development. Our studies have shown that the exposure of Beas-2B cells, a human bronchial epithelial cell line, to lung carcinogenic nickel compounds results in increased COX-2 expression."
"However, the signaling pathways leading to nickel-induced COX-2 expression are not well understood. In the...
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Source: Gene Therapy Weekly (2011-08-04)
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