Gene Therapy

New Gene Therapy Study Results Reported from Medical University of South Carolina

Published in Gene Therapy Weekly, August 4th, 2011

2011 AUG 4 -- "Murine models are ideal for studying cochlear gene transfer, as many hearing loss-related mutations have been discovered and mapped within the mouse genome. However, because of the small size and delicate nature, the membranous labyrinth of the mouse is a challenging target for the delivery of viral vectors," researchers in Charleston, South Carolina report.

"To minimize injection trauma, we developed a procedure for the controlled release of adeno-associated viruses (AAVs) into the scala media of adult mice. This procedure poses minimal risk of injury to structures of the cochlea and middle ear, and allows for near-complete preservation of...

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Source: Gene Therapy Weekly (2011-08-04)

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