Gene Therapy
Investigators at Harvard University Target Gene Therapy
Published in Gene Therapy Weekly, August 25th, 2011
2011 AUG 25 -- Data detailed in "Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs" have been presented. "Persistence of human immunodeficiency virus (HIV) despite highly active antiretroviral therapy (HAART) is a lasting challenge to virus eradication. To develop a strategy complementary to HAART, we constructed a series of Rev-dependent lentiviral vectors carrying diphtheria toxin A chain (DT-A) and its attenuated mutants, as well as human tumor necrosis factor receptor-associated factor 6 (TRAF6)," researchers in Boston, Massachusetts report.
"Expression of these...
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Source: Gene Therapy Weekly (2011-08-25)
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