Sulfides

Findings from University of California in Sulfides Reported

Published in Gene Therapy Weekly, September 1st, 2011

2011 SEP 1 -- According to the authors of a study from Santa Barbara, California, "Gene therapy provides powerful new approaches to curing a large variety of diseases, which are being explored in ongoing worldwide clinical trials. To overcome the limitations of viral gene delivery systems, synthetic nonviral vectors such as cationic liposomes (CLs) are desirable."

"However, improvements of their efficiency at reduced toxicity and a better understanding of their mechanism of action are required. We present the efficient synthesis of a series of degradable multivalent cationic lipids (CMVLn, n=2 to 5) containing a disulfide bond spacer between headgroup and...

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Source: Gene Therapy Weekly (2011-09-01)

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