Gene Therapy
Investigators at Purdue University Target Gene Therapy
Published in Gene Therapy Weekly, September 15th, 2011
2011 SEP 15 -- Investigators publish new data in the report "Adenoviral vector immunity: its implications and circumvention strategies. 'Adenoviral (Ad) vectors have emerged as a promising gene delivery platform for a variety of therapeutic and vaccine purposes during last two decades. However, the presence of preexisting Ad immunity and the rapid development of Ad vector immunity still pose significant challenges to the clinical use of these vectors," scientists in West Lafayette, Indiana report.
"Innate inflammatory response following Ad vector administration may lead to systemic toxicity, drastically limit vector transduction efficiency and significantly...
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Source: Gene Therapy Weekly (2011-09-15)
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