Gene Therapy
Research on Gene Therapy Detailed by Scientists at INSERM
Published in Gene Therapy Weekly, September 22nd, 2011
2011 SEP 22 -- Current study results from the report, "Adeno-associated viral vector-mediated transgene expression is independent of DNA methylation in primate liver and skeletal muscle," have been published. "Recombinant adeno-associated viral (rAAV) vectors can support long-term transgene expression in quiescent tissues. Intramuscular (i.m.) administration of a single-stranded AAV vector (ssAAV) in the nonhuman primate (NHP) results in a peak protein level at 2-3 months, followed by a decrease over several months before reaching a steady-state," scientists writing in the journal Plos One report.
"To investigate transgene expression and vector...
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Source: Gene Therapy Weekly (2011-09-22)
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