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Gene Therapy

New Findings from University of Dundee in the Area of Gene Therapy Published

Published in Gene Therapy Weekly, September 22nd, 2011

2011 SEP 22 -- Research findings, "Keratin 14-null cells as a model to test the efficacy of gene therapy approaches in epithelial cells," are discussed in a new report. "Skin fragility disorders caused by keratin mutations are incurable, and a better understanding of their etiology is needed to find new ways to improve and treat these conditions. The best-studied skin fragility disorder is epidermolysis bullosa simplex (EBS), an autosomal dominant condition caused by mutations in keratin 5 (K5) or K14," investigators in Dundee, United Kingdom report.

"To analyze disease mechanisms and develop gene therapy strategies, we have used keratinocyte cell lines...

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