Gene Therapy

Researchers from Massachusetts Institute of Technology Discuss Findings in Gene Therapy

Published in Gene Therapy Weekly, September 22nd, 2011

2011 SEP 22 -- "The delivery of nucleic acids has the potential to revolutionize medicine by allowing previously untreatable diseases to be clinically addressed. Viral delivery systems have shown immunogenicity and toxicity dangers, but synthetic vectors have lagged in transfection efficiency," scientists writing in the journal Bioconjugate Chemistry report.

"Previously, we developed a modular, linear dendritic block copolymer architecture with high gene transfection efficiency compared to commercial standards. This rationally designed system makes use of a cationic dendritic block to condense the anionic DNA and forms complexes with favorable...

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Source: Gene Therapy Weekly (2011-09-22)

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