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Prostate Cancer

Studies from Texas Tech University Provide New Data on Prostate Cancer

Published in Gene Therapy Weekly, September 29th, 2011

2011 SEP 29 -- New investigation results, "PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor/phospholipase A2 and regulation of NF'B and PPAR," are detailed in a study published in Cytokine. According to the authors of a study from Lubbock, Texas, "Interleukin-8 (IL8/CXCL8) has been described as a key effector in prostate cancer progression and resistance to standard chemotherapeutic drugs. In the present study, we investigated the effect of the natural, angio-inhibitory and anti-tumoral Pigment Epithelium-Derived Factor (PEDF) on the expression of IL8 cytokine by prostate cancer cells."

"Using a cytokine antibody array and...

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