Published in Gene Therapy Weekly, September 29th, 2011
"Six pig-tailed macaques (Macaca nemestrina) underwent total body irradiation and reconstitution with autologous stem cells genetically modified by a gammaretroviral vector overexpressing HOXB4. Two animals were euthanized owing to irradiation-or transplantation-associated toxicity, whereas the other 4 had successful reconstitution. Of the 4 macaques with successful...
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