Opioid Receptors
Investigators at Dartmouth College Target Opioid Receptors
Published in Gene Therapy Weekly, October 20th, 2011
2011 OCT 20 -- Investigators publish new data in the report "Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and mu opioid receptor protein expression while enhancing perivascular microglial ED2. 'Anti-nociceptive tolerance to opioids is a well-described phenomenon, which severely limits the clinical efficacy of opioids for the treatment of chronic pain syndromes. The mechanisms that drive anti-nociceptive tolerance, however, are less well understood," scientists in Hanover, New Hampshire report.
"We have previously shown that glia have a central role in the development of morphine tolerance and that administration of a...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2011-10-20)
More Articles from Gene Therapy Weekly
- Gastroenterology
Data from Sojo University Provide New Insights into Gastroenterology - Hepatitis C Virus
Data from University of Tokyo Advance Knowledge in Hepatitis C Virus - Gene Therapy
Data on Gene Therapy Reported by Researchers at University of Minnesota - Adeno-Associated Virus
Findings in Adeno-Associated Virus Reported from University Hospital - Arthritis
Harvard University Details Research in Arthritis - Small Interference RNAs (siRNAs)
Investigators at Agency for Science Technology and Research Zero in on Small Interference RNAs (siRNAs) - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
