Endocrine-Related Cancer
Research from University of Rennes Has Provided New Data on Endocrine-Related Cancer
Published in Gene Therapy Weekly, October 20th, 2011
2011 OCT 20 -- According to the authors of recent research published in the journal Endocrine-Related Cancer, "The involvement of the coxsackie and adenovirus receptor (CAR), an adhesion molecule known to be the main determinant of adenovirus transduction of the cells, in cancer is currently under investigation. Recent reports suggest that CAR levels are elevated in breast cancer, and this may have an impact on its use as means of delivery for gene therapy."
"In this study, we show that estradiol (E-2) treatment of the estrogen receptor (ER)-positive breast cancer cell MCF-7 increases CAR levels and, in turn, enhances adenoviral transduction....
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Source: Gene Therapy Weekly (2011-10-20)
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